HARMONYCA®

HArmonyCa is a sterile dermal implant:
- Apirogenic, viscous, opaque, injectable, semi-solid, latex-free and biodegradable.
- Immediate lifting effect.
- CaHA microspheres promote collagen synthesis, improving skin quality in the months following treatment.
- Lasting results.
- Lidocaine in the product serves to reduce pain during treatment.

- ALLERGAN
- NAME: HARMONYCA
- COMPOSITION: Calcium hydroxyapatite microspheres 25-45 microns in diameter (55.7%), cross-linked sodium hyaluronate gel (20 mg/mL), phosphate buffer. Lidocaine hydrochloride (3 mg/mL).
- PRESENTATION: 2 x 1.25 ml.
- NEEDLES: 2 x 27G ½”;
- INDICATIONS: HArmonyCa is the solution for patients with skin laxity, loss of elasticity, loss of volume, moderate to severe wrinkles and photo-ageing, smoking and acne damage on the face.
- INJECTION DEPTH: Subcutaneous and intradermal injection into the deep dermis in specific areas of the face.
- DURATION: Up to 18 months.
- USE: Strict medical use.

- Syringes: 2 x 1.25 ml.
- Needles: 2 x 27G ½”;
- Each package contains 2 pre-filled syringes of HArmonyCa 1.25 ml, 2 needles (27G ½”;) reserved exclusively for HArmonyCa injection, the package insert and labels for product traceability.

It is used to define and sculpt facial contours, particularly the jaw line and chin, and to restore lost volume and improve cheek projection.

Calcium hydroxyapatite microspheres 25-45 microns in diameter (55.7%), cross-linked sodium hyaluronate gel (20 mg/mL), phosphate buffer. Lidocaine hydrochloride (3 mg/mL).

- Use only by authorised physicians competent in dermal filling procedures.
- Only for injection into deep dermal or subdermal tissue, according to correct technique; avoid intravascular injection.
- Do not use in areas where tissue is compromised: scars, cartilage, injured skin, infection, active inflammation.
- Prior to injection, take a thorough history and assess the patient's history, particularly conditions that may interfere with healing or increase risk (e.g. coagulation disorders, use of anticoagulants, immunosuppression).
- Maintain sterile conditions: use disposable syringes, sterile devices, do not reuse.
- Avoid intense activity, direct or artificial sun exposure, extreme temperatures, intense massage in the treated area for at least the first 24-48 hours.
- Inform the patient of possible local effects: erythema, oedema, pain, itching, small papules; if they persist or worsen, consult the doctor.
- Caution when combining treatments with other fillers or dermal therapies: the safety of co-administration is not fully established.
- Store the product between +2 °C and +25 °C, avoid freezing and prolonged exposure to light or high temperatures.

HArmonyCa is contraindicated in the following cases:
- In patients with known sensitivity to any of the components of the product.
- In patients with skin pathology or abnormal skin conditions.
- In patients with infection or inflammation (acute or chronic) in or near the treatment site.
- In patients with a tendency to form keloids, hypertrophic scars or develop inflammatory skin conditions.
- In patients with impaired healing due to systemic disease, drugs or poorly vascularised tissue.
- In patients with prolonged bleeding or slowed tissue gain due to medical conditions or medication.
- In patients with a history of anaphylactic reactions and/or multiple severe allergies.
- In patients with known sensitivity to steroids or who are contraindicated to steroid treatment.
That is: not for injection in the glabellar or periocular region, in the lips or perioral area, in regions containing foreign bodies, in patients with herpes or autoimmune diseases.
- In pregnant or breastfeeding women.
- In subjects < 18 years.

Dual action in facial rejuvenation. Its formula combines hyaluronic acid (HA), which provides immediate hydration and volume, with calcium hydroxyapatite (CaHA), which stimulates natural collagen production, improving the structure and elasticity of the skin over time.

The contents of the HArmonyCa syringe are sterilised by steam.